Sabetian Natural Appearance Clinic

Soraya Sabetian

Registered Nurse

Dermal Fillers

The Smart Choice of HA Dermal Filler 


Dermal filler can help to instantly restore your skin’s volume and smooth away facial wrinkles and folds. Minimally invasive procedures,  injectable dermal fillers can plump thin lips, enhance shallow contours, soften facial creases, remove wrinkles and improve the appearance of recessed scars.

Dermal filler is an injectable gel made from hyaluronic acid (HA) a naturally occurring substance in your skin. Some dermal fillers contain a local anaesthetic that provides more comfort both during and after injection. 

What is Hyaluronic Acid (HA)?

Hyaluronic acid (HA) is a naturally occurring polymer found in all living organisms.  The human dermis has a high percentage of HA, which hydrates the skin because of its high water-binding properties. HA is the predominant part of the viscoelastic intracellular matrix, which provides and maintains proper tissue volume and acts as a cushion to help protect the skin. The natural product, if injected into the skin, would be rapidly lost. To produce a longer-lasting HA, it must be made more robust and stable by cross-linking.  * Cross-linked gels combine with naturally occurring HA to provide volume and support for 4 to 12 months.

Some areas that Dermal Filler can be injected are:

  • Cheeks -  add volume to deflated and sunken cheeks, and to define cheekbones 

  • Marionette Lines - To fill and reduce their appearance 

  • Jawline - to soften sharp or overly angular jawlines. 

  • Lips - add volume and definition to thin or shrunken lips. Also to reduce the appearance of wrinkles around the lip area. 

  • Nasolabial lines / folds - To reduce the appearance of deep lines between the bottom of the nose and corners of the mouth

Hyaluronic Acid Dermal Filler, Neuramis® is the for deep and fixed wrinkles, volume and rejuvenation of the skin. Neuramis® products are manufactured using Medytox’s unique double’ cross-linking technology, SHAPE technology, to be made stable gels. It minimizes uncross-linked BDDE and guarantees 3 values.

SHAPE Technology of Neuramis®, the ideal HA dermal filler, is manufactured using SHAPE technology which Medytox has developed. 

SHAPE(Stabilized Hyaluronic Acid & Purification Enhancement)

3 Values of Neuromis

After your complimentary consultation, you will be booked in for an appointment to be treated. The chosen Neuramis dermal filler will be injected by fine needles or administered by using a Microcannula. 

The difference between Dermal filler and Botulinum toxin is that a dermal filler is an injectable gel that provides volume where as, Botulinum toxin relaxes muscle activity and is used to treat moderate to severe lines caused by repeated facial expressions.

*Cross-linking is a chemical process of bonding one polymer chain to another to create a larger, more stable molecule.

Reference1. Born T. Hyaluronic acids. Clin Plast Surg 2006; 33:525-38.2. Carruthers A, Carruthers J. Non-animal based hyaluronic acid fillers: scientific and technical considerations. Plast Reconstr Surg 2007;120:33S.3. Tmothy C Flynn. Comparative Histology of Intradermal Implantation of Mono and Biphasic   Hyaluronic Acid Fillers. Dermatol Surg 2011;37:1-7.

Dermal Fillers are a gel containing hyaluronic acid that is injected into or below the skin by a healthcare professional to smooth facial wrinkles and enhance lips by restoring volume and fullness. Do not have Dermal Filler injections in an area where there is a non resorbable implant or if you have irritated or infected skin, allergy to hyaluronic acid or other severe allergies, autoimmune disorders or hypersensitivity to local anesthetic or porphyria. Caution if you have a bleeding disorder, if you take medicines that prolong bleeding time, have had poor results with previous similar injections, have angina combined with rheumatism or a tendency to large scar formation. Dermal Filler treatments may result in some redness, swelling, pain or tenderness, itching and/or bruising which may last a few days. Inflammatory reactions can last up to two weeks in rare cases. See your healthcare professional if any side effects concern you. Exposure to excessive sunlight or extreme cold should be avoided until redness or swelling has resolved. Dermal Fillers are not recommended for people taking blood thinning medicines and they have not been tested.